Which protein solubility kit should I use for my protein target: OptiSol 30 or 200?
The OptiSol™ Protein Solubility Screening kit is compatible with a wide diversity of protein particle sizes ranging from <1 kDa to 30 kDa and from >30kDa up to 200 kDa. The Kit should be selected according to the expected MW of the solubilized protein particle:
Kit
Size Specifications and Recommendations
OptiSol 30
For peptides or proteins less than 30 kDa when monomeric
For oligomeric complexes with a total molecular weight less than 30 kDa
OptiSol 200
For proteins less than 200 kDa when monomeric
For oligomeric complexes with a total molecular weight less than 200 kDa
